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Disease Insect Models Equipment Supplied In Europe
29 equipment items found
Manufactured by:Systasy Bioscience GmbH based inMunich, GERMANY
DiseasePROFILER employs Pathway-centric lead discovery in pooled cohorts using multi-level barcoding strategies. The DiseasePROFILER uses a subset of top-performing sensors identified in the PathwayPROFILER assay and enables simple, robust, and cost-effective screening of compound effects in human disease models. ...
Manufactured by:GENFIT based inLoos, FRANCE
We are conducting a research program to develop an anti-fibrotic drug candidate, with a priority given to liver fibrosis. This program consists in a repositioning of Nitazoxanide, or NTZ*, that is being investigated for the treatment of fibrosis in pre-clinical disease models. NTZ is currently being evaluated in an investigator-initiated proof-of-concept clinical trial for the potential ...
Manufactured by:IMG Pharma Biotech S.L. based inDerio - Bizkaia, SPAIN
Parkinsonized Macaca Fascicularis Primate Cell Membrane Microarray, Pack of 1 slide containing cell membranes extracted from several tissues/organs, depending on the ...
Manufactured by:Yashraj Biotechnology Ltd based inNavi Mumbai, INDIA
Neural Progenitor Cells (NPCs) are multipotent cells derived from iPSCs that are self-renewing and have the potential to differentiate into various neuronal lineages. This makes them very attractive for in vitro patient-specific ...
by:Healx Ltd. based inCambridge, UNITED KINGDOM
Our Rare Treatment Accelerator helps academic, patient, and industry groups advance their rare disease drug redevelopment projects. By combining our team, expertise and financial resources with your research and insights, we can get treatments to patients ...
Manufactured by:leadXpro AG based inVilligen, SWITZERLAND
Using X-ray structure-based molecular design, leadXpro has discovered, optimised and patented two new series of selective antagonists of the A2B adenosine receptor. ...
Manufactured by:CN Bio based inCambridge, UNITED KINGDOM
Arranged in a multi-well format, the PhysioMimix™ MPS-LC12 plate has 12 independent ...
Manufactured by:Allevi, Inc. based inPhiladelphia, PENNSYLVANIA (USA)
Clinically relevant drug-drug interactions (DDI) are a serious concern for any new drug development project. To better support capturing the multiple mechanisms of DDI potential using primary hepatocytes, we now offer Interaction Qualified Human Hepatocytes (Catalog HUCPI) which are characterized for 3 major mechanisms of DDI: transporter activity, enzyme activity, and induction potential, ...
by:Reaction Biology Corp. based inMalvern, PENNSYLVANIA (USA)
In collaboration with the bioinformatics firm 4HF Biotech GmbH which is a bioinformatics firm specializing in cancer data mining to discover new anti-cancer drugs, we offer data mining for analysis of the genetic signature of tumor cell lines that are sensitive for a customer drug to reveal potential biomarkers. The Biomarker Analysis is based on the sensitivity profile of the customer compound ...
Manufactured by:PhenoSys GmbH based inBerlin, GERMANY
The optomotor response (OMR) is a reflex used to assess visual function. The PhenoSys qOMR (quantitative optomotor response) is a unique system that automatically measures the OMR with minimal experimenter effort. It uses a virtual stimulation cylinder that continuously aligns with the animal´s head position. Based on real-time head tracking, quantitative OMR measurements run fully ...
Manufactured by:InSphero AG based inSchlieren, SWITZERLAND
The 3D InSight™ Steatosis Model is an advanced human disease model that enables you to screen compounds and investigate disease pathophysiology using a physiologically relevant human liver microtissue that recapitulates the first stage of non-alcoholic fatty liver disease: accumulation of lipids in liver hepatocytes. Available as an assay-ready model delivered to your lab, or for use ...
Manufactured by:Alcyomics Ltd. based inNewcastle Upon Tyne, UNITED KINGDOM
Disease specific in vitro models for your research. Skimune AD: Our advanced Skimune® model stimulated to demonstrate an AD phenotype through addition of inflammatory cytokines and autologous immune ...
Manufactured by:Mimetas B.V. based inLeiden, NETHERLANDS
OrganoReady® Colon Caco-2 offers 38 ready-to-use Caco-2 tubules for drug exposure, transport, and permeability studies. The product is based on the OrganoPlate® 3-lane 40 with 3 adjacent channels per chip, including one perfused Caco-2 tubule. OrganoReady® Caco-2 comprises 38 ready-to-use Caco-2 tubules for drug exposure, transport, and permeability studies. Do you want to perform ...
Manufactured by:Mimetas B.V. based inLeiden, NETHERLANDS
OrganoReady® Blood Vessel HUVEC comprises 38 ready-to-use HUVEC tubules for drug exposure, transport, and permeability studies. The product is based on the OrganoPlate® 3-lane 40 with 3 adjacent channels per chip, including one perfused HUVEC tubule. Do you want to perform experiments in human-relevant, complex 3D tissue models but don’t have the time or experience to build your ...
by:bit.bio based inCambridge, UNITED KINGDOM
Introducing highly-defined, consistent and reliable human muscle cells for research, disease modelling and high throughput screening across areas such as muscle, neuromuscular, and associated metabolic disorders. ioSkeletal Myocytes have been reprogrammed from human induced pluripotent stem cells (iPSCs) using our precise reprogramming technology: ...
Manufactured by:Auris Medical AG based inBasel, SWITZERLAND
The OligoPhore™ / SemaPhore™ technology has been extensively and successfully tested with various siRNA and mRNA sequences in numerous disease models in mice. For the development of our first proprietary drug product, AM-401 (OligoPhore™ siRNA targeting KRAS), we have initiated a program of IND-enabling ...
Manufactured by:Mimetas B.V. based inLeiden, NETHERLANDS
OrganoReady® Angiogenesis HUVEC comprises 64 HUVEC tubules ready-to-sprout. The product is based on the OrganoPlate® 3-lane 64 with 3 adjacent channels per chip, including one perfused HUVEC tubule. Do you want to perform experiments in human-relevant, complex 3D tissue models but don’t have the time or experience to build your own? Look no further, with the OrganoReady Angiogenesis ...
Manufactured by:Ncardia Services B.V. based inLeiden, NETHERLANDS
Vascular endothelial cells are involved in multiple processess including blood flow, vascular permeability or angiogenesis. Our team can manufacture endothelial cells from the iPSC line that best fits your project with a controlled and scalable process. Custom assays can be developed with this fully functional cell model to screen drug-induced effects on endothelial barrier permeability or 3D ...
Manufactured by:Ncardia Services B.V. based inLeiden, NETHERLANDS
Astrocytes are essential players in neurodegenerative disease progression providing a valuable tool for drug discovery and disease modeling. Human iPSC-derived astrocytes generated with our standardized process express key identity markers and support co-culture with human iPSC-derived neurons. Our team can manufacture astrocytes at scale from the iPSC that best fits your project or work with ...
Manufactured by:Ncardia Services B.V. based inLeiden, NETHERLANDS
Cortical neurons play a vital role in many neurodegenerative diseases, including Alzheimer’s disease. Human iPSC-derived cortical neurons can be co-cultured with astrocytes and microglia to model neurodegenerative diseases. Our team can manufacture cortical neurons at scale from the iPSC line that best fits your project or work with off-the-shelf Ncyte Cortical Neurons to support your drug ...