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Disease Modeling Equipment Supplied In Europe
29 equipment items found
Manufactured by:Ncardia Services B.V. based inLeiden, NETHERLANDS
The discovery that transformed biological research. In 2007, Shinya Yamanaka and Kazutoshi Takahashi were able to reprogram human somatic cells into pluripotent stem cells by inducing the expression of four embryonic transcription factors. The resultant cells were called human induced pluripotent stem cells (iPSC). iPSCs have unlimited proliferation capacity and can be differentiated into nearly ...
Manufactured by:Systasy Bioscience GmbH based inMunich, GERMANY
The DiseasePROFILER uses a subset of top-performing sensors identified in the PathwayPROFILER assay and enables simple, robust, and cost-effective screening of compound effects in human disease models. ...
Manufactured by:GENFIT based inLoos, FRANCE
This program consists in a repositioning of Nitazoxanide, or NTZ*, that is being investigated for the treatment of fibrosis in pre-clinical disease models. NTZ is currently being evaluated in an investigator-initiated proof-of-concept clinical trial for the potential treatment of NASH-induced significant liver fibrosis. For more information, go to clinical ...
by:bit.bio based inCambridge, UNITED KINGDOM
Introducing highly-defined, consistent and reliable human muscle cells for research, disease modelling and high throughput screening across areas such as muscle, neuromuscular, and associated metabolic disorders. ioSkeletal Myocytes have been reprogrammed from human induced pluripotent stem cells (iPSCs) using our precise reprogramming technology: ...
by:Reaction Biology Corp. based inMalvern, PENNSYLVANIA (USA)
The Biomarker Analysis tool identifies genes or genetic alterations which are indicative for the efficacy of a drug and which may serve as predictive biomarkers in disease models and patient ...
Manufactured by:Auris Medical AG based inBasel, SWITZERLAND
The OligoPhore™ / SemaPhore™ technology has been extensively and successfully tested with various siRNA and mRNA sequences in numerous disease models in mice. For the development of our first proprietary drug product, AM-401 (OligoPhore™ siRNA targeting KRAS), we have initiated a program of IND-enabling ...
Manufactured by:InSphero AG based inSchlieren, SWITZERLAND
The 3D InSight™ Steatosis Model is an advanced human disease model that enables you to screen compounds and investigate disease pathophysiology using a physiologically relevant human liver microtissue that recapitulates the first stage of non-alcoholic fatty liver disease: accumulation of lipids in ...
Manufactured by:Hemogenyx Pharmaceuticals plc based inLondon, UNITED KINGDOM
Originally developed for in-house testing, the company’s Advanced peripheral blood Hematopoietic Chimera (“ApbHC”) is a novel type of humanised mouse that presents several advantages over existing mouse models. It has applications for disease modelling and drug development, and potentially for ...
Manufactured by:Ncardia Services B.V. based inLeiden, NETHERLANDS
Astrocytes are essential players in neurodegenerative disease progression providing a valuable tool for drug discovery and disease modeling. Human iPSC-derived astrocytes generated with our standardized process express key identity markers and support co-culture with human iPSC-derived neurons. Our team can manufacture astrocytes at scale ...
Manufactured by:InSphero AG based inSchlieren, SWITZERLAND
Test efficacy of anti-NASH drugs in an advanced 3D human liver disease model. The InSphero 3D InSight™ Human Liver NASH Model consists of an advanced microtissue co-culture of healthy primary human liver cells combined with specially formulated media and cocktails that induce the progression of NAFLD and NASH from steatosis to liver ...
Manufactured by:IMG Pharma Biotech S.L. based inDerio - Bizkaia, SPAIN
Parkinsonized Macaca Fascicularis Primate Cell Membrane Microarray, Pack of 1 slide containing cell membranes extracted from several tissues/organs, depending on the ...
Manufactured by:Yashraj Biotechnology Ltd based inNavi Mumbai, INDIA
Neural Progenitor Cells (NPCs) are multipotent cells derived from iPSCs that are self-renewing and have the potential to differentiate into various neuronal lineages. This makes them very attractive for in vitro patient-specific ...
by:Healx Ltd. based inCambridge, UNITED KINGDOM
Our Rare Treatment Accelerator helps academic, patient, and industry groups advance their rare disease drug redevelopment projects. By combining our team, expertise and financial resources with your research and insights, we can get treatments to patients ...
Manufactured by:leadXpro AG based inVilligen, SWITZERLAND
Using X-ray structure-based molecular design, leadXpro has discovered, optimised and patented two new series of selective antagonists of the A2B adenosine receptor. ...
Manufactured by:CN Bio based inCambridge, UNITED KINGDOM
Arranged in a multi-well format, the PhysioMimix™ MPS-LC12 plate has 12 independent ...
Manufactured by:Allevi, Inc. based inPhiladelphia, PENNSYLVANIA (USA)
Clinically relevant drug-drug interactions (DDI) are a serious concern for any new drug development project. To better support capturing the multiple mechanisms of DDI potential using primary hepatocytes, we now offer Interaction Qualified Human Hepatocytes (Catalog HUCPI) which are characterized for 3 major mechanisms of DDI: transporter activity, enzyme activity, and induction potential, ...
Manufactured by:PhenoSys GmbH based inBerlin, GERMANY
The optomotor response (OMR) is a reflex used to assess visual function. The PhenoSys qOMR (quantitative optomotor response) is a unique system that automatically measures the OMR with minimal experimenter effort. It uses a virtual stimulation cylinder that continuously aligns with the animal´s head position. Based on real-time head tracking, quantitative OMR measurements run fully ...
Manufactured by:Alcyomics Ltd. based inNewcastle Upon Tyne, UNITED KINGDOM
Disease specific in vitro models for your research. Skimune AD: Our advanced Skimune® model stimulated to demonstrate an AD phenotype through addition of inflammatory cytokines and autologous immune ...
Manufactured by:Mimetas B.V. based inLeiden, NETHERLANDS
OrganoReady® Colon Caco-2 offers 38 ready-to-use Caco-2 tubules for drug exposure, transport, and permeability studies. The product is based on the OrganoPlate® 3-lane 40 with 3 adjacent channels per chip, including one perfused Caco-2 tubule. OrganoReady® Caco-2 comprises 38 ready-to-use Caco-2 tubules for drug exposure, transport, and permeability studies. Do you want to perform ...
Manufactured by:Mimetas B.V. based inLeiden, NETHERLANDS
OrganoReady® Blood Vessel HUVEC comprises 38 ready-to-use HUVEC tubules for drug exposure, transport, and permeability studies. The product is based on the OrganoPlate® 3-lane 40 with 3 adjacent channels per chip, including one perfused HUVEC tubule. Do you want to perform experiments in human-relevant, complex 3D tissue models but don’t have the time or experience to build your ...