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Physiological Relevance Equipment Supplied In Europe
19 equipment items found
by:Thermo Fisher Scientific, LIMS & Laboratory Software based inPhiladelphia, PENNSYLVANIA (USA)
Create physiologically relevant cell culture models. Gibco Human Plasma-like Medium (HPLM) is a new formulation designed to resemble the natural cellular environment found in the body, mimicking the metabolic profile of human plasma. The widely used classic synthetic cell culture media, including MEM, DMEM, RPMI 1640, and DMEM/F-12 contain glucose, amino acids, ...
Manufactured by:InSphero AG based inSchlieren, SWITZERLAND
The 3D InSight™ Steatosis Model is an advanced human disease model that enables you to screen compounds and investigate disease pathophysiology using a physiologically relevant human liver microtissue that recapitulates the first stage of non-alcoholic fatty liver disease: accumulation of lipids in liver hepatocytes. Available as an assay-ready model ...
Manufactured by:Mimetas B.V. based inLeiden, NETHERLANDS
The product is based on the OrganoPlate® 3-lane 40 with 3 adjacent channels per chip, including one perfused HUVEC tubule. Do you want to perform experiments in human-relevant, complex 3D tissue models but don’t have the time or experience to build your own? Look no further, with the OrganoReady Blood Vessel HUVEC you can now take your vascular research to the next ...
Manufactured by:Mimetas B.V. based inLeiden, NETHERLANDS
OrganoReady® Caco-2 comprises 38 ready-to-use Caco-2 tubules for drug exposure, transport, and permeability studies. Do you want to perform experiments in human-relevant, complex 3D tissue models but don’t have the time or experience to build your own? Look no further, with the OrganoReady Colon Caco-2 you can now easily take your intestinal research to the next level. ...
Manufactured by:Kirkstall Ltd. based inYork, UNITED KINGDOM
The QV500 cell culture chamber is a highly flexible research tool, ideal for academic use. Produced from medical-grade silicone, the chamber provides a leak proof seal, allowing continuous flow of media across and through cell cultures. The chamber has a common diameter with the wells in standard 24-well plates, allowing for protocols developed for static cultures to easily be transferred to the ...
Manufactured by:Ncardia Services B.V. based inLeiden, NETHERLANDS
Alterations in the functionality of vascular smooth muscle cells are associated with the progression of pathological conditions such as inflammation, atherosclersosis or pulmonary hypertension. Our team manufactures, at scale, vascular smooth muscle cells derived from the iPSC line that best fits your project. This in vitro model provides reliable predictions on vasoactivity compound-induced ...
Manufactured by:mimiX Biotherapeutics based inBiel/Bienne, SWITZERLAND
Biologicals – Cells, spheroids, organoids- or non-biological particles are dispersed in a hydrogel precursor and loaded in the SIM carrier. A vertical vibration generated with sound is applied, and a pattern is generated within seconds. Crosslinking of the patterned particulates within the hydrogel is carried out by using different stimuli (light, enzymatic, thermal crosslinking) ...
Manufactured by:CN Bio based inCambridge, UNITED KINGDOM
Our Non-Alcoholic Fatty Liver Disorder (NAFLD)/NASH in vitro Services offer a preclinical tool to test therapeutics in a human-relevant model, replicating key disease phenotypes including fibrosis and reporting clinical biomarkers to allow translatability to clinical trials. ...
Manufactured by:mimiX Biotherapeutics based inBiel/Bienne, SWITZERLAND
Create biological architectures with sound. Sound Induced Morphogenesis (SIM) is a gentle, fast, and easy method to generate multi-cellular, spatially orchestrated tissue constructs using sound waves. This versatile method addresses necessities in the broad field of life sciences, finding application in tissue engineering, regenerative medicine, or pharmaceutical research for drug ...
Manufactured by:Mimetas B.V. based inLeiden, NETHERLANDS
OrganoReady® Angiogenesis HUVEC comprises 64 HUVEC tubules ready-to-sprout. The product is based on the OrganoPlate® 3-lane 64 with 3 adjacent channels per chip, including one perfused HUVEC tubule. Do you want to perform experiments in human-relevant, complex 3D tissue models but don’t have the time or experience to build your own? Look no further, with the OrganoReady Angiogenesis ...
Manufactured by:Ncardia Services B.V. based inLeiden, NETHERLANDS
Vascular endothelial cells are involved in multiple processess including blood flow, vascular permeability or angiogenesis. Our team can manufacture endothelial cells from the iPSC line that best fits your project with a controlled and scalable process. Custom assays can be developed with this fully functional cell model to screen drug-induced effects on endothelial barrier permeability or 3D ...
Manufactured by:Ncardia Services B.V. based inLeiden, NETHERLANDS
Astrocytes are essential players in neurodegenerative disease progression providing a valuable tool for drug discovery and disease modeling. Human iPSC-derived astrocytes generated with our standardized process express key identity markers and support co-culture with human iPSC-derived neurons. Our team can manufacture astrocytes at scale from the iPSC that best fits your project or work with ...
Manufactured by:Ncardia Services B.V. based inLeiden, NETHERLANDS
Angiogenesis, the sprouting of new blood vessels from pre-existing vasculature, plays an important role in the maintenance of body homeostasis and the progression of cancer and Alzheimer’s disease, among others. Studying vessel formation can help identify and validate targets and candidates for treatment of a variety of diseases. Using Ncardia’s human iPSC-derived endothelial cells, ...
Manufactured by:Ncardia Services B.V. based inLeiden, NETHERLANDS
Cortical neurons play a vital role in many neurodegenerative diseases, including Alzheimer’s disease. Human iPSC-derived cortical neurons can be co-cultured with astrocytes and microglia to model neurodegenerative diseases. Our team can manufacture cortical neurons at scale from the iPSC line that best fits your project or work with off-the-shelf Ncyte Cortical Neurons to support your drug ...
Manufactured by:Ncardia Services B.V. based inLeiden, NETHERLANDS
The discovery that transformed biological research. In 2007, Shinya Yamanaka and Kazutoshi Takahashi were able to reprogram human somatic cells into pluripotent stem cells by inducing the expression of four embryonic transcription factors. The resultant cells were called human induced pluripotent stem cells (iPSC). iPSCs have unlimited proliferation capacity and can be differentiated into nearly ...
Manufactured by:ANB sensors based inHaslingfield, UNITED KINGDOM
ANBSensors has teamed up with Stemnovate to build a smart ‘Liver on a Chip’ platform, enhancing drug ...
Manufactured by:Ncardia Services B.V. based inLeiden, NETHERLANDS
Human-induced pluripotent stem cell (iPSC) derived atrial cardiomyocytes are a powerful tool to improve in vitro testing of new treatments for atrial arrhythmias. Our team can manufacture atrial cardiomyocytes at the scale needed from the iPSC that best fits your project, ensuring high purity and consistency between batches. Custom assays can be developed based on this model to support your large ...
Manufactured by:InSphero AG based inSchlieren, SWITZERLAND
Test efficacy of anti-NASH drugs in an advanced 3D human liver disease model. The InSphero 3D InSight™ Human Liver NASH Model consists of an advanced microtissue co-culture of healthy primary human liver cells combined with specially formulated media and cocktails that induce the progression of NAFLD and NASH from steatosis to liver inflammation and fibrosis. Ideal for investigating ...
Manufactured by:CN Bio based inCambridge, UNITED KINGDOM
Generate human-specific pre-clinical safety and efficacy data with pioneering PhysioMimix single- and multi-organ-on-a-chip ...
