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In Vivo Models Equipment & Supplies Near Canada
77 equipment items found
Manufactured by:Inovotion Sas based inLa Tronche, FRANCE
INOVOTION has developed a unique, highly sensitive and reproducible assay. It is applicable to all preclinical oncology and immuno-oncology drug discovery programs, and monitors the growth and metastatic dissemination of human tumor ...
Manufactured by:Acuitas Therapeutics based inVancouver, BRITISH COLUMBIA (CANADA)
Acuitas specializes in the development of lipid nanoparticle delivery systems for molecular therapeutics. Our scientists have synthesized over 500 novel cationic lipids which have been evaluated in in vivo models including non-human primate (NHP) models. This evaluation characterizes the potency and safety of these LNP carriers for delivery ...
Manufactured by:InnoSer Belgie NV based inDiepenbeek, BELGIUM
Slow progression with cysts in all segments of the ...
Manufactured by:Absolute Antibody Ltd based inRedcar, UNITED KINGDOM
Recombinant monoclonal antibody to Amphibian Allergen. Manufactured using AbAb’s Recombinant Platform with variable regions (i.e. specificity) from the hybridoma ...
Manufactured by:InnoSer Belgie NV based inDiepenbeek, BELGIUM
Slow and reproducible cyst formation in the proximal part of the ...
Manufactured by:InnoSer Belgie NV based inDiepenbeek, BELGIUM
Quick progression of cyst formation in the distal segment of the ...
Manufactured by:Xtant Medical based inBelgrade, MONTANA (USA)
The graft does not adhere to gloves yet maintains its placement in the surgical environment. Osteoinductivity of sterile final product is assessed in vivo. In this challenging model, every lot tested to date has consistently demonstrated an osteoinductive response. This performance validates Xtant Medical’s expertise in DBM processing. ...
by:Oligomerix, Inc. based inWhite Plains, NEW YORK (USA)
Our lead compound, known as OLX07010, is a small molecule inhibitor of tau self-association which has demonstrated in vivo efficacy in two transgenic mouse models of tauopathy, htau and JNPL3, representing tau aggregation in AD and inherited tauopathies, respectively. ...
by:Celluris based inSão Paulo, BRAZIL
The Celluris’ novel solution, named RfuCAR, was engineering in order to respond some challenges addressed by clinical trials around the world. RfuCAR is a bispecific in tandem receptor CAR, that is composed by an antigen binding domain and another domain that binds to an extracellular molecule from tumoral microenvironment. ...
by:Zucara Therapeutics Inc. based inToronto, ONTARIO (CANADA)
Zucara Therapeutics is developing ZT-01, a first-in-class, once-daily therapeutic to prevent insulin-induced hypoglycemia in patients using insulin therapy. ZT-01 is designed to inhibit somatostatin, a pancreatic hormone that impairs the glucagon response to hypoglycemia in people with insulin dependent diabetes. ZT-01 restores glucagon secretion to prevent hypoglycemia, which could dramatically ...
by:Geistlich Pharma North America Inc. based inPrinceton, NEW YORK (USA)
User Benefits: Geistlich Fibro-Gide® is a porcine, porous, resorbable and volume-stable collagen matrix, specifically designed for soft-tissue regeneration.1,4,10 The collagen matrix is made of reconstituted collagen and undergoes smart chemically cross-linking to improve its volume stability while maintaining a good biocompatibility.1-3,4-10 The porous network of Geistlich Fibro-Gide® ...
Manufactured by:Auris Medical AG based inBasel, SWITZERLAND
The OligoPhore™ / SemaPhore™ technology has been extensively and successfully tested with various siRNA and mRNA sequences in numerous disease models in mice. For the development of our first proprietary drug product, AM-401 (OligoPhore™ siRNA targeting KRAS), we have initiated a program of IND-enabling ...
Manufactured by:Destiny Pharma plc based inBrighton, UNITED KINGDOM
There are two XF-73 dermal programmes in development. One is being run by our China partner and shareholder – China Medical Systems Holdings Limited (CMS) – focused on superficial skin infections and the other is an in-house programme looking at the use of XF-73 for the prevention and treatment of serious infections associated with burns and open wounds such as diabetic foot ulcers ...
Manufactured by:Emulate based inBoston, MASSACHUSETTS (USA)
Study drug absorption and drug-drug interactions in a primary organoid-based model of the human small ...
Manufactured by:Elpiscience based inShanghai, CHINA
ES014 is a first-in-class anti-CD39xTGF-β bispecific antibody (bsAb) that simultaneously targets the adenosine and TGF-β pathways, two major immunosuppressive mechanisms in the tumor microenvironment (TME). Solid tumors frequently express TGF-β, which suppresses T cell activation and induces CD39 expression, the rate-limiting enzyme in the ATP-adenosine pathway. The anti-CD39 ...
Manufactured by:Immatics N.V. based inTuebingen, GERMANY
Bispecific T cell engaging receptors (TCER®) are off-the-shelf biologics that leverage the body’s immune system by redirecting and activating T cells towards cancer cells expressing specific tumor targets. The design of these novel biologics allows any T cell in the body to become activated and attack the tumor, regardless of the T cells’ intrinsic ...
Manufactured by:Yeasen Biotechnology (Shanghai) Co.,Ltd. based inShanghai, CHINA
Ceturegel Matrix is a soluble basement membrane preparation extracted from EHS mouse tumors rich in extracellular matrix proteins. Its main components are laminin, type IV collagen, heparan sulfate proteoglycan (HSPG), nestin as well as growth factors such as TGF-beta, EGF, IGF, FGF, tissue plasminogen activator, and other growth factors contained in EHS tumors. Yeasen provides diverse kinds of ...
by:In2Bones Global based inMemphis, TENNESSEE (USA)
Synergistic Combination of Bioactive Glass and Demineralized Bone Matrix. Bioactive Matrix is a novel bone graft substitute expressly designed to optimize surgical handling, graft stability and osteoproductivity. ...
by:Oncodesign based inDijon, FRANCE
This is the best tool you can use to evaluate new therapeutic approaches in conditions that are as close as possible to a clinical situation: ...
Manufactured by:Yeasen Biotechnology (Shanghai) Co.,Ltd. based inShanghai, CHINA
Ceturegel basement membrane matrix is a soluble basement membrane preparation extracted from EHS mouse tumors rich in extracellular matrix proteins. Ceturegel™ GFR (Phenol Red-Free&LDEV-Free) is a low growth factor matrix obtained after special treatment, which can effectively ensure the needs of some experimental operations that require low growth factors, such as experiments related ...