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Epitope Services
31 services found
Manufactured by:Sanquin based inAmsterdam, NETHERLANDS
Our proprietary technology for UV-induced MHC-peptide exchange is ideally suited for high-throughput screening of peptide-binding to the MHC class I complexes. Moreover, combinatorial coding enables fast finding of relevant peptide-specific cytotoxic T ...
Manufactured by:POP Biotechnologies, Inc. (POP BIO) based inBuffalo, NEW YORK (USA)
CoPoP GLP toxicity report available. CoPoP is part of EuCorVac-19, tested in a 280 person ph1/2 trial. Testing framework for human ...
Manufactured by:POP Biotechnologies, Inc. (POP BIO) based inBuffalo, NEW YORK (USA)
SNAP liposomes contain synthetic MPLA, QS-21 and Cobalt porphyrin phospholipid (CoPoP). CoPoP enables liposomes to stably bind short MHC-I epitopes upon admixture. Better delivery of epitopes and adjuvants to immune cells in draining lymph nodes. Induce higher frequency of antigen specific CD8+ T cells with > 10,000X lower peptide ...
Manufactured by:Creative Biolabs based inShirley, NEW YORK (USA)
Creative Biolabs provides a comprehensive range of services based on our matured platform, which involves in the custom antibody development service, from antigen design and epitope prediction to antibody purification and labeling. https://modelorg-ab.creative-biolabs.com/monoclonal-antibody-development.htm ...
Manufactured by:Aviva Systems Biology Corporation based inSan Diego, CALIFORNIA (USA)
Surface Plasmon Resonance (SPR) is a powerful analytical technology that is well suited for analyzing and characterizing antibodies. SPR can be used to measure the antibody-antigen binding kinetics, perform epitope binning and epitope mapping. The latter may be used to identify antibody pairs for developing high-precision ELISA or multiplex assays.. Aviva Systems ...
Manufactured by:Absolute Antibody Ltd based inRedcar, UNITED KINGDOM
Binding multiple epitopes with a single antibody offers several benefits. For example, one specificity may target individual molecules while another could recruit effector cells or deliver a drug to the target. Other options include dual-target bispecifics which might detect a desired cell type with much higher selectivity than a monospecific antibody. ...
by:Biointron based inShanghai, CHINA
Nanobodies are distinguished from other conventional antibody formats by their unique properties of size, solubility, intrinsic stability, easy tailoring into pluripotent constructs, recognition of uncommon or hidden epitopes, binding into cavities or active sites of enzyme targets, ease and speed of drug discovery, and ease of manufacture. BioIntron is a well-recognized leader ...
Manufactured by:Antibodies Incorporated based inDavis, CALIFORNIA (USA)
The monoclonal antibodies produced have broad utility as therapeutics, diagnostic tools, and research reagents. The approach enables discovery of antibodies that bind to a variety of epitopes on the target molecule and, coupled with a robust screening platform, allows for identification of clones with the most desirable characteristics. ...
by:MtoZ Biolabs based in, MASSACHUSETTS (USA)
T cells play a vital role in destroying pathogens and monitoring pathological cells. They are able to distinguish between self-antigens and non-self-antigens by surface T cell receptors (TCRs). Most human T cells express the classical TCRs, which consists of TCRα and TCRβ chains co-expressed with CD3 chains (γ, δ, ε, and ζ). ...
Manufactured by:MODAG GmbH based inWendelsheim, GERMANY
The misfolding/ aggregation pathway resulting in amyloid fibrils involves characteristic oligomer species which have been shown to be the most relevant toxic protein species. These pathological oligomers exhibit structural epitopes that are not found in physiologically folded proteins or physiological protein assemblies, providing a specific structural target for anle138b, our ...
Manufactured by:Rockland Immunochemicals, Inc. based inLimerick, PENNSYLVANIA (USA)
Our list of services includes antigen consultation, peptide or protein antigen production, antibody generation, antibody purification, and conjugation to reporter molecules such as peroxidase or fluorochromes. We are experts in generating antibodies specific for post-translational modifications—including phospho-epitopes, acetylation, methylation, hydroxylation, ...
by:Revvity Gene Delivery (formerly SIRION Biotech) based inHamburg, GERMANY
In the discovery of oncology therapeutics, Antibody-drug conjugates (ADCs) are rapidly gaining momentum, with hundreds of candidates advancing through clinical development. Whether your priority lies in assessing the epitope binding of your construct, evaluating the cytotoxic potency of the payload, or scrutinizing the efficacy of the linker in cleaving, each facet demands ...
Manufactured by:Nexelis based inSeattle, WASHINGTON (USA)
We have exceptional in vitro bioassay development services and support for early evaluation and screening of candidate therapeutics. Our highly experienced team will facilitate in silico immunogenicity assessment with epitope prediction to in vitro immunogenicity and immuno-functionality assays. ...
by:MtoZ Biolabs based in, MASSACHUSETTS (USA)
Monoclonal antibodies (mAbs) are powerful therapeutic tools. These glycoproteins, belonging to the immunoglobulin (Ig) family, are utilized by the immune system to identify and neutralize foreign organisms or antigens. Ig’s are classified in five groups, IgA, IgD, IgE, IgG, and IgM (as α, δ, ε, γ, and μ), based on the structure of their constant regions. Among these, IgG subtypes—predominantly ...
by:Ab Studio Inc. based inHayward, CALIFORNIA (USA)
3D Computer-aided antibody structure analysis service based on advanced AI protein modeling software (AlphaFold) and antibody design ...
by:Ab Studio Inc. based inHayward, CALIFORNIA (USA)
1D antibody sequence analysis service with licensed software and in-house ...
by:MtoZ Biolabs based in, MASSACHUSETTS (USA)
Monoclonal antibodies (mAbs) are monovalent proteins expressed by B cells, capable of precisely targeting 3D epitopes, which makes it a compelling therapeutic option. Over 70 monoclonal antibody drugs have received FDA approval. Monoclonal antibody drugs dramatically transform modern medicine by offering targeted treatments for a variety of diseases. ...
Manufactured by:POP Biotechnologies, Inc. (POP BIO) based inBuffalo, NEW YORK (USA)
Nanograms of peptide reverse established and metastatic tumor rowth in TC-1 tumor model. Other cancer models show synergy with checkpoint blockade inhibition and other anti-tumor treatments. ...
Manufactured by:Bioventix Plc based inSurrey, UNITED KINGDOM
Bioventix has created a novel sheep hybridoma technology to produce stable and productive cell lines that secrete sheep monoclonal antibodies (SMAs) of very high affinity. The ultra-high affinity of Bioventix’s antibodies facilitates the development of immunoassays of increased sensitivity and precision at Bioventix’s ...
Manufactured by:Creative Biolabs based inShirley, NEW YORK (USA)
Label-free interaction analysis is of great importance for scientists to study interactions between biomolecules. Scientists from Creative Biolabs are competent for performing antibody affinity and kinetics measurement with the most advanced Biacore, ProteOn, Octet systems, etc. These systems are mainly based on the optical phenomena technologies - surface plasmon resonance (SPR) and bio-layer ...