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In Vitro Micronucleus Test Services
23 services found
Manufactured by:Gentronix Ltd based inCheshire, UNITED KINGDOM
The in vitro micronucleus test (MNT) is a main-stay of most regulatory genotoxicity testing strategies, and is used to detect in vitro clastogens and aneugens. In this regard it complements the Ames test well, as between the two study types they detect all of the three major classes of ...
Manufactured by:CD Formulation based in, NEW YORK (USA)
Microspheres & Microneedles In Vitro Release Testing: For biodegradable materials, swelling and erosion mechanisms are also major factors controlling drug release. The composition, pH value, ionic strength, osmotic pressure and temperature of the release medium will all affect the release rate. The measurement of microsphere and microneedle in vitro release test provided by CD Formulation is to ...
by:Wintermute Biomedical based inScoresby, AUSTRALIA
Wintermute launched the Doxall™ Sanitiser range in 2021 and has multiple other therapeutic formulations in its development pipeline. These including a Covid 19 preventative and treatment inhalant and a topical shingles therapeutic. Wintermute formulations demonstrate exceptional potential for the treatment of infections. Some key advantages of ...
by:Envigo based inCambridgeshire, UNITED KINGDOM
A Phase I study is a safety trial in a small number of healthy human volunteers or patients. It is typically the first human exposure to a New Chemical Entity (NCE) and takes place in a controlled clinical setting. To be granted permission by the regulatory bodies to perform such a study, a comprehensive package of toxicology data, demonstrating safety at many times the human dose in animals, ...
Manufactured by:Creative Bioarray based inShirley, NEW YORK (USA)
Advances had been made towards the use of in vitro human skin equivalents/models for dermal drug and cosmetic product testing. In vitro Skin Models (Human Skin Equivalent, FTSK, HSE) used under defined test conditions offer several advantages: i) since most models are composed of primary human cells, inter-species extrapolation is avoided; ii) in contrast to human skin specimens, repeated ...
Manufactured by:Shenzhen AIVD Biotechnology Co. , LTD. based inCheektowaga, NEW YORK (USA)
AIVD Biotech has established three R&D divisions: IVD Raw Materials, Immunodiagnostic and Molecular Diagnostic Test ...
Manufactured by:CN Bio based inCambridge, UNITED KINGDOM
Employing our Liver-on-a-chip hepatic co-culture model (evaluated by our collaborators at the U.S. FDA), our DILI in vitro Service can screen your small molecules, antibodies, ASO, and gene editing reagents to establish human DILI ...
by:Inotiv based inWest Lafayette, INDIANA (USA)
You’ve worked hard to get this far. Rely on Inotiv’s scientific leadership and attentive, decisive advice to uncover potential flaws in your novel pharmaceutical compound that might limit its development — before you invest significant time and ...
Manufactured by:Newcells Biotech Limited based inNewcastle Upon Tyne, UNITED KINGDOM
Accelerated in vitro evaluation of retinal toxicity. Newcells offers a fast and reliable retinal drug toxicity in vitro testing service using complex models developed in house: retinal organoids and RPE. The retinal toxicity service evaluates how new compounds affect cell viability, following photoreceptor degeneration or loss of RPE barrier function including outer segment photoreceptor ...
Manufactured by:Resonetics based inNashua, NEW HAMPSHIRE (USA)
Minimally invasive therapeutic and diagnostic medical products for: Electrophysiology cardiology, radiology, cryotherapy, drug delivery, pulmonology, gastroenterology, pain management, neurology. Catheter-orientated manufacturing process development. Supply chain selection, management, and technical oversight. In-vivo study protocol development, execution, reporting. Clinical site initiation, ...
by:iFyber, LLC based inIthaca, NEW YORK (USA)
iFyber specializes in evaluating the effects of new biomaterials, medical devices, and investigational compounds on mammalian biological systems. We are focused on implementing high throughput, repeatable, relevant, and quantitative in vitro assays that provide clients with robust data from which to plan future product development and verification ...
Manufactured by:Alfa Scientific Designs, Inc based inPoway, CALIFORNIA (USA)
ALFA offers development services to include contract product development. technology transfer, and various technological offerings such as latex, lateral flow, and fluorescent methodologies. ALFA develops breakthrough designs produced to the highest quality standards and provides a complete solution for customer specific design, assay development, laboratory and clinical sample testing. ...
by:Trion Research GmbH based inPuchheim, GERMANY
We combine leading scientific expertise in tumor immunology and virus-induced immune disorders with dedicated analytical know-how. Our services comprise Liquid Biopsy diagnostics with the analysis of virus-infected cells and the detection of disseminated tumor cells in blood, urine and other body fluids. Moreover, we offer the full range of preclinical and clinical support from trial design over ...
Manufactured by:Alcyomics Ltd. based inNewcastle Upon Tyne, UNITED KINGDOM
Preclinical safety and efficacy testing of drugs as “first in man studies”, sensitisation testing of chemicals and cosmetics, safety and efficacy testing of cellular therapies. Human in vitro tests as alternative to animal models. ...
by:iFyber, LLC based inIthaca, NEW YORK (USA)
iFyber provides a suite of biofilm tests to verify the efficacy of antimicrobial medical devices and drugs. Biofilms are complex communities of microbes protected within a matrix of sugars, proteins, and extracellular DNA. These characteristics, in addition to their tolerance to antibiotics, make biofilms significantly more difficult to prevent and remove. Research has shown that between 60 to ...
Manufactured by:Charles River based inHollister, CALIFORNIA (USA)
From complete IND-enabling programs to stand-alone assessments, our Safety Assessment team provides a full range of in vivo and in vitro testing services and regulatory support to comply with worldwide regulatory restrictions for the nonclinical development of pharmaceuticals, medical devices and animal health products as well as chemicals, agrochemicals, and biocides. Our scientific and ...
by:Oncodesign based inDijon, FRANCE
Establishing proof of concept in preclinical pharmacology is a critical step in the drug discovery process. This is one of the decisive factors in setting the therapeutic indication(s) targeted in clinical models and in the decision to continue a new product through the regulatory preclinical and clinical steps. For more than 25 years, Oncodesign has been a player known for its experience and ...
by:MtoZ Biolabs based in, MASSACHUSETTS (USA)
In the biological activities of organisms, the function of proteins is achieved through interactions between proteins. Therefore, studying new protein interactions can provide new directions for investigating the potential functions of proteins. Among many protein interaction identification experiments, pull-down is commonly used for in vitro protein interaction testing, and helps discover new ...
by:TÜV SÜD America Inc. based inWakefield, MASSACHUSETTS (USA)
In the medical field, practitioners utilize a range of devices to address patient health, from diagnosis to surgery. When the patient comes into contact with a medical device or material, it should fulfill its intended function without harming the patient. Therefore, all medical devices need to undergo a thorough biological risk assessment to protect the patient from any toxic, physiological, ...
Manufactured by:Cloud-Clone Corp. based inKaty, TEXAS (USA)
Pharmacokinetics mainly study dynamic changes of drug metabolism in body, including drug absorption, distribution and excretion. The research will analyze the drugs and their metabolites by collecting samples in different tissues, organs at different time point. The pharmacokinetic experiments in vivo and in vitro can be designed according to customers’ ...