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Neurodegeneration Services In North America
19 services found
Manufactured by:Creative Biogene-Mitochondrial Research based inNY, NEW YORK (USA)
Neurodegenerative diseases (NDs) comprise a diverse set of pathological processes involving progressive neuronal dysfunction, degeneration, and death, leading to incurable and debilitating diseases. Creative Biogene provides a comprehensive range of services and products to assist researchers in neurodegeneration-related mitochondria ...
Manufactured by:vivoVerse Inc. based inAustin, TEXAS (USA)
C. elegans is recognized as a useful alternative in vivo model. The vivoChip® enables the use of C. elegans for high-content, multi-parametric analysis of neurodegeneration phenotypes from high-resolution fluorescence images of neurons. To demonstrate our unique capabilities, we studied dendritic neurodegeneration of dopaminergic neurons in C. elegans induced ...
Manufactured by:Creative Bioarray based inShirley, NEW YORK (USA)
Human iPSC-derived Microglia provide a reproducible, physiologically-relevant model in an easy-to-use, assay-ready format for investigating neuroglia involvement in neurodegeneration and neurodevelopment. We also offer a fully optimized serum-free Microglia Maintenance Medium to promote and support the maintenance of microglia. The method for generating iPSC-derived microglia ...
Manufactured by:Creative Biolabs based inShirley, NEW YORK (USA)
The C. elegans model is suitable for the research of bioactive compounds in various fields, such as anti-aging research, anti-neurodegeneration, anti-obesity, anti-infection and intestinal health. Besides those, the technological development of C. elegans in other fields is also extensive, such as instrumental analysis and emerging methods. Creative Biolabs can provide customized ...
Manufactured by:Creative Biogene based inShirley, NEW YORK (USA)
Moreover, autophagy has been highlighted as a crucial component of pathological processes such as cancer, hypoxia, pathogen infection, and neurodegeneration. Thus, the estimation of the rate of autophagy in a quantitative manner, especially in in vivo models, has become a vital need in the field. AAV Production ...
by:IOS Press based inAmsterdam, NETHERLANDS
Here you will find information about our ejournals and ebooks in terms of collections/subject areas, pricing, terms and conditions and a FAQ ...
Manufactured by:Creative Biolabs based inShirley, NEW YORK (USA)
Amyotrophic lateral sclerosis is a neurodegenerative disorder leading to loss of voluntary muscle movement, paralysis, and eventually death. There is now an urgent need for the development of effective treatment for ALS. ...
Manufactured by:Creative Biogene-Mitochondrial Research based inNY, NEW YORK (USA)
Creative Biogene provides the fractionated mitochondrial magnetic separation (FMMS) method to increase the production of brain-derived mitochondria compared with the UC method and can better detect mitochondrial damage in the central nervous system injury and neurodegenerative ...
Manufactured by:RareStone Group based inShanghai, CHINA
Rare neurological diseases include developmental defects of the nervous system, genetic and metabolic diseases, neuroimmune diseases, neurological tumors, special types of infectious diseases of the nervous system, neurodegenerative diseases, and neuromuscular diseases. At present, more than 7,000 rare diseases have been found in humans, about 60% of which are neurological diseases. ...
Manufactured by:Creative Biolabs based inShirley, NEW YORK (USA)
Autophagy is a key catabolic process that ensures the removal of excess or damaged cellular components under physiological and pathological conditions, and provides a metabolic supply in the absence of extracellular nutrients, thereby maintaining the proper balance of cells. Optimal autophagy activity plays an important protective role in several human diseases, such as neurodegenerative ...
Manufactured by:Creative Biolabs based inShirley, NEW YORK (USA)
Multiple Sclerosis (MS) is a chronic inflammatory neurodegenerative disease of the central nervous system (CNS). Experimental autoimmune encephalomyelitis (EAE) is the most common animal model of human MS as it is especially useful to investigate neuroinflammatory pathways and often serves as a "proof-of-principle" model for the efficacy of novel treatment strategies. ...
Manufactured by:Neurodigitech, LLC based inEncinitas, CALIFORNIA (USA)
The NDT teams in specialized in both non-GLP and GLP compliant pre-clinical assessments of CNS disease therapeutics using a variety of biomarkers, including histology, immunohistochemical and histochemical methods. In particular, NDT is dedicated to custom-designed neuropathological assessments for the neurodegenerative diseases, such as Alzheimer's, Parkinson's, ALS, and brain insults (strokes ...
Manufactured by:Advanced Brain Monitoring, Inc. based inCarlsbad, CALIFORNIA (USA)
Advanced Brain Monitoring provides full service EEG for clinical trials using the StatX Series wireless EEG systems administered concurrently with a full suite of tasks, including resting state and event-related related protocols. Stat X24 combines rapid application, low patient burden and disposable materials with high quality EEG acquisition easily performed in a clinical or home setting. Our ...
by:MtoZ Biolabs based in, MASSACHUSETTS (USA)
Gangliosides are a large class of complex lipids that are abundant in the neuronal cell membranes in the brain. These molecules consist of sphingolipids with one or more sialic acids attached to the sugar chain. As structural components of cell membranes, gangliosides have their two hydrocarbon chains embedded in the plasma membrane, while the oligosaccharides are located on the cell surface, ...
Manufactured by:Ozgene Pty Ltd. based inBentley DC, AUSTRALIA
Knockout mice are animal models that have been genetically modified to delete or inactivate a specific gene. The term ‘knockout’ refers to knocking out the functionality of the target gene. These mouse models allow researchers to gain insight into how the loss of the gene affects physiology, behavior and disease development. Observing the characteristics of a knockout phenotype can ...
by:MtoZ Biolabs based in, MASSACHUSETTS (USA)
"Knocking out" related mammalian genes is an important method for studying gene function or its potential as a drug target, widely used in research on neurodegenerative diseases such as Alzheimer's disease, cancer, cardiovascular diseases, inflammation, or metabolic diseases. CRISPR/Cas9 is a revolutionary gene-editing technology that can precisely modify the genomic sequence. ...
by:MtoZ Biolabs based in, MASSACHUSETTS (USA)
Prostanoids, also known as eicosanoids, are a family of signaling molecules produced and secreted by various types of cells under both normal and pathological conditions. In the human body, these metabolites are excreted into body fluids such as plasma and urine. The precursors of prostanoids are 20-carbon polyunsaturated fatty acids (PUFAs) like arachidonic acid (C20:4), which are esterified in ...
Manufactured by:Arthus Biosystems, LLC based inChantilly, VIRGINIA (USA)
S-adenosylmethionine (SAM) is an important molecule in methionine cycle pathway and one carbon metabolism pathway that are implicated in many metabolic abnomalities found in humans. Methylation index is defined as the ratio of SAM and SAH, which is a better way to evaluate methylation status of humans and other organisms. The level of S-adenosylmethionine (SAM) fluctuates depending on age, ...
Manufactured by:Arthus Biosystems, LLC based inChantilly, VIRGINIA (USA)
Our team of scientists performs integrated research, development, and technical support to market the antibodies against S-adenosylmethionine, or the SAM molecule. We are dedicated to develop several formats of immunoassays to detect SAM and S-adenosylhomocysteine (SAH) from biosamples efficiently. Immunoassays have been approved to be easy to use without requiring costly equipment, ...