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Therapeutic Development Equipment & Supplies
64 equipment items found
by:CrystalsFirst GmbH based inMarburg, GERMANY
FragAI is an automated workflow for generation of active molecules for therapeutics development using chemoinformatics, bioinformatics and machine learning. Our methodology uses the data flow from SmartSoak and FastForward output. The step of fragment hit expansion and evolution builds on validated fragment hits. ...
Manufactured by:ASC Therapeutics based inMilpitas, CALIFORNIA (USA)
Genome editing technologies enables permanent modifications to the genome by harnessing the activities of certain enzymes (e.g. nucleases and integrase) and invoking DNA repair mechanisms at specific locations in the genome. As a therapeutic modality, genome editing can correct a defective gene, disrupt a deleterious gene, or target a therapeutic gene to a ...
by:Cyrus Biotechnology Inc. based inSeattle, WASHINGTON (USA)
Novel IL-2 approaches and technologies are driving innovation in the therapeutic development space. The IL-2 pathway influences critical aspects of both immune stimulation and immune regulation, through the development and expansion of regulatory T cells ...
by:Caribou Biosciences, Inc. based inBerkeley, CALIFORNIA (USA)
Natural killer (NK) cells, as their name implies, play an important role in ridding the body of cancer and viruses. NK cells are emerging as an increasingly important cell type for therapeutic development. Solid tumors are particularly challenging to treat and CAR-T cells have largely underperformed in the solid tumor setting. NK cells, however, inherently ...
Manufactured by:Genscript based inPiscataway, NEW JERSEY (USA)
cPass Neutralization Antibody Detection kit detects circulating neutralizing antibodies against SARS-CoV-2 that block the interaction between the receptor binding domain (RBD) of the viral spike glycoprotein with the ACE2 cell surface receptor. This kit would be instrumental in vaccine and therapeutic development as it is suitable for all antibody isotypes and ...
Manufactured by:Realize Therapeutics Corp. based inLake Bluff, ILLINOIS (USA)
SIBO is a condition related to excess numbers of bacteria in the small intestine, and can be linked to Irritable Bowel Syndrome, Research clearly shows that certain microbes are very effective at treating SIBO and related issues. Realize Therapeutics is developing formulas to address these health ...
Manufactured by:Entero Therapeutics, Inc. based inBoca Raton, FLORIDA (USA)
Capeserod is a selective 5-HT4 receptor partial agonist, which Entero Therapeutics is repurposing and developing for multiple GI conditions. Based on the biological evidence of expression of 5-HT4b receptor subtype in human GI tract, Entero Therapeutics believes that capeserod may directly or indirectly initiate the peristaltic or secretory ...
Manufactured by:Evox Therapeutics Limited based inOxford, UNITED KINGDOM
Evox’s proprietary protein engineering technology enables loading of protein therapeutics and tissue targeting moieties onto the surfaces of exosomes, which allows targeting and display of therapeutic proteins to an organ of ...
Manufactured by:PharmAbcine Inc. based inYuseong-gu, SOUTH KOREA
PharmAbcine’s fully human antibody library provides the diversity of antibody candidates for target antigens, ensuring highest success rates of developing therapeutic antibodies for various indications. Our unique and diverse antibody repertoires are constructed by recombination of V gene segments and DJ gene segments in human B-cell derived antibody heavy ...
Manufactured by:ProImmune Ltd. based inOxford, UNITED KINGDOM
Detecting and targeting specific MHC-peptide complexes is of material interest for understanding many disease conditions better and for developing novel therapeutic interventions. It has been very challenging to develop antibodies that bind selectively to an MHC-peptide combination over a more general MHC ...
Manufactured by:Neutron Therapeutics, Inc. based inDanvers, MASSACHUSETTS (USA)
Neutron Therapeutics has developed an accelerator-based, in-hospital neutron source to replace the previously required nuclear reactor. This source is composed of a 2.6 MeV electrostatic proton accelerator and a rotating, solid lithium target for generating neutrons. Neutron Therapeutics will provide this neutron source as part of a comprehensive ...
Manufactured by:Confo Therapeutics based inGhent/Zwijnaarde, BELGIUM
Confo Therapeutics is building a pipeline of drug candidates with the potential to transform therapeutic outcomes for patients with severe illnesses lacking disease-modifying ...
by:Curadigm based inParis, FRANCE
Curadigm’s technology was developed to address a critical challenge facing intravenously administered therapeutics: How can you efficiently deliver a drug to your tissue of interest without rapid clearance? To address this, we developed technology that reduces unwanted hepatic clearance, resulting in a temporary increase in blood ...
Manufactured by:2A Pharma ApS based inAalborg Øst, DENMARK
Head and neck cancers represent the sixth most common cancer worldwide, resulting in more than 350,000 deaths/year. Our AAVLP-HNC vaccine uses our mimotope selection technology and has the potential to minimize side effects, improve efficacy, and markedly reduce treatment costs. This will address an unmet medical need and benefit cancer patients as well as reduce healthcare expenses. In addition, ...
Manufactured by:Great Lakes NeuroTechnologies based inCleveland, OHIO (USA)
By integrating advanced technology with patient-centered design, KinesiaU™ provides objective assessments that can improve clinical outcomes by identifying optimal therapeutic activities. The development of this system by Great Lakes NeuroTechnologies emphasizes a commitment to advancing neurological ...
Manufactured by:Kiadis Pharma NV based inAmsterdam, NETHERLANDS
Accessing a new repertoire of targets. Two classes of molecule with therapeutic potential that are not currently addressed by antibody drugs are G-protein-coupled receptors and ion channels, largely because they display small epitopes not accessible to traditional antibodies and their sequence is often conserved and thus less likely to be ...
by:Sword Diagnostics, Inc. based inCarmel, INDIANA (USA)
Utilizing our proprietary Sword Swift™ Method Development Process and Sword Swift™ Detection Reagents, our scientists can develop sensitive quantitative assays to measure the amounts of free or bound drug in preclinical or clinical samples with high accuracy and ...
by:DxDiscovery, Inc. based inReno, NEVADA (USA)
Production of monoclonal antibodies (mAbs) is central to all efforts at DxDiscovery. MAb production begins with immunization of a mouse with an antigen. Several weeks after immunization, spleen cells are harvested. B cells in the spleen produce antibody but cannot grow in culture. The spleen cells are fused with cells of a myeloma line. The myeloma cells cannot produce antibody, but they will ...
Manufactured by:CELONIC Group based inBasel, SWITZERLAND
An extremely productive and stable CHO-based expression system for biopharmaceuticals. CHOvolution® is a CHO-K1 based expression platform that can be used for a broad range of applications, from non-GMP R&D testing to GMP development and commercial market supply, with a support system to help throughout every step of development. Besides offering cell line development services, Celonic is ...
by:Sword Diagnostics, Inc. based inCarmel, INDIANA (USA)
Sword scientists specialize in the development of qualitative or quantitative bioanalytical methods that measure cellular biomolecules active in a specific disease state. Cell-based assays are bioanalytical methods that measure the presence, amount, or activity of biomolecules in cells, cell fractions, nuclear extracts, tissue extracts, or cell extracts. In pharmaceutical drug ...