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Mtoz Biolabs Rss Services Available In In Usa Virginia
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by:MtoZ Biolabs based in, MASSACHUSETTS (USA)
MtoZ Biolabs provides bile acids analysis service using UPLC/TripleQuad5500, which can quantitatively analyze over 90 kinds of bile ...
by:MtoZ Biolabs based in, MASSACHUSETTS (USA)
Collagen is a basic component of the extracellular matrix and the most abundant protein in the animal body, accounting for about 30% of the total protein. It is a glycoprotein, composed of three polypeptide α-chains with Gly-XY repeating residues (Gly stands for glycine, X for proline, Y for hydroxyproline), and is renowned for its triple helix structure. ...
by:MtoZ Biolabs based in, MASSACHUSETTS (USA)
The process where proteins separated by electrophoresis are transferred or “blotted” from the gel matrix onto a membrane (usually nitrocellulose or polyvinylidene difluoride (PVDF)), followed by subsequent antibody-based detection on the membrane surface, is known as western blot (WB) or immunoblotting. Mtoz Biolabs provides WB analysis ...
by:MtoZ Biolabs based in, MASSACHUSETTS (USA)
Peptidomics refers to the study of all endogenous bioactive peptides in organism, cell, or tissue. Bioactive peptides are biologically active substances involved in various cellular functions within the organism, which include cytokines, growth hormones, and disease-specific degradation fragments of certain proteins in body fluids. ...
by:MtoZ Biolabs based in, MASSACHUSETTS (USA)
KEGG (Kyoto Encyclopedia of Genes and Genomes) database is a database used for systematic analysis of metabolic pathways and functions of gene products in cells. KEGG helps to study genes and its expression information as a whole network. KEGG integrates data from genomes, chemical molecules, and biochemical systems, including metabolic pathways (PATHWAY), drugs (DRUG), diseases (DISEASE), gene ...
by:MtoZ Biolabs based in, MASSACHUSETTS (USA)
Aggregation or fragmentation of protein molecules primarily causes variations in molecular size, impacting their biological activity, stability, and their efficacy and safety as pharmaceuticals. In the development and production of biopharmaceuticals, even slight variations in molecular size can reduce drug efficacy or pose safety risks. Thus, precise detection and analysis of these variations ...
by:MtoZ Biolabs based in, MASSACHUSETTS (USA)
Molecular size variation critically influences the properties of biomacromolecules such as proteins, antibodies, and peptides, especially in the realms of drug research and bioproduct manufacturing. Size Exclusion Chromatography (SEC), also known as Gel Permeation Chromatography (GPC), separates compounds based on molecular size. ...
by:MtoZ Biolabs based in, MASSACHUSETTS (USA)
During the production of bioproducts, it's common to find impurities not only produced in the manufacturing process but also related to the desired products. These product-related impurities typically consist of product variants that do not align functionally with the target product. The most common variants arise from chemical modifications, as well as from the degradation and aggregation of the ...
by:MtoZ Biolabs based in, MASSACHUSETTS (USA)
Metabolic bone disease encompasses a range of bone disorders caused by congenital or acquired factors that disrupt normal bone metabolism and biochemical states, leading to disorders in bone biochemistry and metabolism. These disorders stem from abnormalities in three key areas: bone resorption, bone growth, and mineral deposition. Increasingly, research has identified numerous cytokines involved ...
by:MtoZ Biolabs based in, MASSACHUSETTS (USA)
Cell death occurs through several pathways including apoptosis, necrosis, and other emergent pathways. Apoptosis is pivotal in immune responses, involving processes such as intracellular balance, T cell clustering, the death of reactive lymphocytes, and cytotoxity of target cells. Apoptosis involves key components like APO-1/Fas, a receptor essential for apoptotic signaling; Caspase-3, crucial ...
by:MtoZ Biolabs based in, MASSACHUSETTS (USA)
To maintain the immune system's homeostasis, multiple control systems are essential for managing infections, inhibiting tumor growth, preventing inflammation, and avoiding autoimmune diseases. T cells are known to be critical in this regulatory process. Specifically, Th3 cells primarily secrete TGF-β along with varying levels of IL-4 and IL-10. Natural regulatory T cells and Tr1 cells can ...
by:MtoZ Biolabs based in, MASSACHUSETTS (USA)
Obesity is a systemic disease, not only does it lead to changes in body shape, but it also brings along various diseases and complications, affecting an individual's overall health. Common complications, such as hyperglycemia, hyperlipidemia, and hypertension, are medically termed as "metabolic syndrome". The fluid factors secreted by adipose tissue propel the development of metabolic syndrome ...
by:MtoZ Biolabs based in, MASSACHUSETTS (USA)
During the tumor formation process, cancer cells release various cytokines and growth factors into the surroundings and reprogram many other types of cells to establish a tumor microenvironment. As a result, tumor tissues almost always contain a large number of endothelial cells, fibroblasts, and infiltrating inflammatory cells, which in turn produce various cytokines. Tumor-derived VEGF acts on ...
by:MtoZ Biolabs based in, MASSACHUSETTS (USA)
The gut microbiota, also known as the gut microbiota, refers to the microorganisms that live in the digestive tract of humans and other animals, including bacteria and fungi. In the human body, without gut microbiota, some undigested carbohydrates cannot be consumed because certain types of gut microbiota have enzymes that human cells lack to break down certain polysaccharides. ...
by:MtoZ Biolabs based in, MASSACHUSETTS (USA)
Different fatty acids (FAs) vary greatly in the number of double bonds and the length of their carbon (C) chains. Very long-chain fatty acids (VLCFAs) are fatty acids with more than 20 carbon atoms. VLCFAs are precursors of lipid mediators and are components of cellular lipids such as sphingolipids and glycerophospholipids. ...
by:MtoZ Biolabs based in, MASSACHUSETTS (USA)
Polyprenols are long-chain isoprenoid alcohols. The general formula for polyprenols is H-(C5H8)n-OH, where n refers to the number of isoprene units. Polyprenols are classified into three types: all-trans (solanesol-type), two-trans (Solanesol-type) and poly-cis (Betulaprenol-type), and three-trans and poly-cis (Ficaprenol-type). Despite their low content, polyprenols are natural bioregulators ...
by:MtoZ Biolabs based in, MASSACHUSETTS (USA)
Prostaglandins (PG) are a group of lipid compounds with hormone-like effects that exhibit diverse physiological activities in animals. PG are enzymatically derived from fatty acids with 20 carbon atoms and a 5-carbon ring. They belong to a subfamily of eicosanoids and prostanoid class of fatty acid derivatives. PG have two main derivatives: prostacyclin and thromboxane. Prostacyclin is a potent ...
by:MtoZ Biolabs based in, MASSACHUSETTS (USA)
Polyunsaturated fatty acids (PUFAs) are primarily classified into ω-3 and ω-6 fatty acids. The difference between these two fatty acids lies in the position of the first double bond from the methyl end of the fatty acid chain. ω-6 fatty acids have a carbon-carbon double bond at the n-6 ...
by:MtoZ Biolabs based in, MASSACHUSETTS (USA)
Gangliosides are a large class of complex lipids that are abundant in the neuronal cell membranes in the brain. These molecules consist of sphingolipids with one or more sialic acids attached to the sugar chain. As structural components of cell membranes, gangliosides have their two hydrocarbon chains embedded in the plasma membrane, while the oligosaccharides are located on the cell surface, ...
by:MtoZ Biolabs based in, MASSACHUSETTS (USA)
Carbon metabolism analysis in MtoZ Biolabs encompasses both one carbon metabolism and central carbon metabolism. The metabolism of certain amino acids can produce groups containing a carbon, known as one carbon unit (C1 unit). These groups can participate in biosynthesis upon transfer. The metabolic processes involving the production and transfer of C1 unit are referred to as one carbon ...