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Creative Biogene Medical Services Near New Zealand
90 services found
Manufactured by:Creative Biogene based inShirley, NEW YORK (USA)
Adenoviral vectors have the potential to be extremely valuable tools for human gene therapy. It has been used to infect many mammalian cell types (both replicative and non-replicative) for high expression of the recombinant protein. Recombinant adenoviruses are especially useful for gene transfer and protein expression in cell lines. During adenovirus vector production, particles may be generated ...
Manufactured by:Creative Biogene based inShirley, NEW YORK (USA)
CpG oligodeoxynucleotides (CpG ODN) is a synthetic oligodeoxynucleotide, containing unmethylated CpG motifs derived from bacterial DNA, with immunostimulatory activities. Several studies have shown that CpG ODN is able to stimulate cells that express TLR9, initiating an immunomodulatory cascade that culminates in the production of Th1 and proinflammatory cytokines and ...
Manufactured by:Creative Biogene based inShirley, NEW YORK (USA)
Model plant is a species that has been widely studied. With its characteristics like dwarf phenotype, short life cycle, fertility and small genome, model plant plays a crucial role in plant genomics research. Model plant is highly homologous with other complex plants in molecular level. Therefore, genome research of model plant establishes a foundation to reveal the functional genomics of higher ...
Manufactured by:Creative Biogene based inShirley, NEW YORK (USA)
Creative Biogene is one of the leading biotechnology companies which has the expertise and ability in providing custom siRNA Screening Service for customers worldwide. Creative Biogene's sophisticated equipments, advanced technologies and highly experienced staffs are available to provide you the complete siRNA screening service including whole genome-wide siRNA Screening or gene set siRNA ...
Manufactured by:Creative Biogene based inShirley, NEW YORK (USA)
Plants provide an inexpensive and simple system for the production of valuable recombinant proteins on large scale. Comparing with the conventional microbial and animal cell culture systems, plant-based system has numerous of clear advantages such as flexibility to rapidly scale up, reduced input costs, appropriate post-translational modifications, and absence of potential risks of contamination ...
Manufactured by:Creative Biogene based inShirley, NEW YORK (USA)
The sponge mRNA contains multiple target sites complementary to a miRNA of interest. Stably expressed miRNA sponge is particularly valuable for long-term loss-of-function studies both in vitro and in vivo. Creative Biogene provides world-class MicroRNA (miRNA) sponge service and we have been perfecting MicroRNA sponge service for many years. Our microRNA sponge is a RNA molecule with 5-8 tandem ...
Manufactured by:Creative Biogene based inShirley, NEW YORK (USA)
Lentiviruses are powerful tools that have been widely used to efficiently transduce both replicating and quiescent cells. The regular lentiviruses are well-known for possessing the ability to stably integrate into their target cell genomes as proviruses. Integrase-deficient lentivirus (IDLV), also known as non-integrating lentivirus (NILV), is a novel technology derived from the regular ...
Manufactured by:Creative Biogene based inShirley, NEW YORK (USA)
Creative Biogene has established fully-matured RNAi system, ranges from design, siRNA synthesis/shRNA construction, transfection, expression evaluation to functional testing. On this basis, we offer cell-based RNAi service to verify the silencing effects of siRNA transient transfection and/or shRNA incorporation and stable expression. Creative Biogene has the ability to accurately evaluate the ...
Manufactured by:Creative Biogene based inShirley, NEW YORK (USA)
Genomic engineering in cell lines is a versatile tool for studying gene function, designing diseases models, biopharmaceutical research, drug discovery and many other applications. CRISPR (Clustered Regulatory Interspaced Short Palindromic Repeats)/Cas9 systems is a newly developed yet the most popular method for genome editing. It has been widely used in current biology, functional genome ...
Manufactured by:Creative Biogene based inShirley, NEW YORK (USA)
Creative Biogene has developed a series of Cas9 expressing stable cell lines. The Cas9 encoding gene is stably integrated into either random site, or AAVS1 safe harbor site of human genome, or ROSA26 safe harbor site of mouse genome. Apart from HEK293 and HeLa cells, we have achieved Cas9 stable expression in several types of cancer cells which makes it convenient for scientists to study related ...
Manufactured by:Creative Biogene-Mitochondrial Research based inNY, NEW YORK (USA)
Creative Biogene has developed a series of technical service platforms for mitochondrial dynamics monitoring and analysis. Our experienced professional team uses advanced technology to provide customers with the most comprehensive mitochondrial research services to help with the breakthrough in mitochondrial ...
Manufactured by:Creative Biogene-Mitochondrial Research based inNY, NEW YORK (USA)
Creative Biogene's experienced team of scientists provides customers with efficient mitochondrial exome sequencing services and the most professional technical support. We provide exome targeting technology designed to produce comprehensive bioinformatics solutions by customizing different sequencing depths for common and rare mutations in mitochondrial ...
Manufactured by:Creative Biogene-Mitochondrial Research based inNY, NEW YORK (USA)
The Creative Biogene's detection platform uses biochemical methods to efficiently and accurately detect the activities of mitochondrial respiratory chain complex and ATP enzyme. Results can help screen mitochondrial respiratory chain complex inhibitors quickly and ...
Manufactured by:Creative Biogene based inShirley, NEW YORK (USA)
Autophagy is a catabolic mechanism which sequesters cytoplasmic components for lysosomal-mediated degradation, including protein inclusions and damaged organelles. Autophagy has an important role in diverse physiological processes such as adaptation to nutrient starvation, cell death, embryonic development, energy metabolism, and antigen presentation, among other events. Moreover, autophagy has ...
Manufactured by:Creative Biogene based inShirley, NEW YORK (USA)
Creative Biogene CRISPR/Cas9 PlatformCB has established a cost-effective, high-throughput strategy for identifying CRISPR/Cas-induced on/off-target mutations via deep sequencing of PCR amplicons. Based on years of experience in genome editing and off-target effects analysis, we offer one-stop solution to accurately detecting mutations induced by sequence-specific nucleases. Our talent scientists ...
Manufactured by:Creative Biogene based inShirley, NEW YORK (USA)
Recently developed CRISPR/Cas9-based screening methods have great potential for revealing the mechanisms and treatment strategies of human diseases, but there are still some biological studies that are not suitable for CRISPR knockout screening. CRISPRa and CRISPRi screening opens up many new possibilities. CRISPR/Cas9 PlatformCB provides custom libraries for any set of genes of interest, as ...
Manufactured by:Creative Biogene based inShirley, NEW YORK (USA)
GFP Reporter Cell Line-HT1080 is engineered to stably overexpress GFP reporter gene. It is an ideal positive control for use in fluorescence assays. In addition, HT1080 cells form tumors post implantation into immunocompromised mice. The in vivo growth of these tumors can be monitored using optical imaging. ...
Manufactured by:Creative Biogene based inShirley, NEW YORK (USA)
GFP Reporter Cell Line-4T1.2 is clonally derived from 4T1.2 cell line which was transduced by a lentiviral vector containing GFP and puromycin resistance gene. GFP is expressed as free cytoplasmatic proteins in these 4T1.2-GFP stable cells. It is a ready-to-use in vitro model for cell-based assay applications. ...
Manufactured by:Creative Biogene based inShirley, NEW YORK (USA)
GFP Stable Cell Line-SW480 was derived from colon of a 50 year-old male with colorectal adenocarcinoma. SW480 is negative for CSAp (CSAp-) and colon antigen 3 and are positive for keratin by immunoperoxidase staining. There is a G to A mutation in codon 273 of the p53 gene resulting in an Arg to His substitution and a C to T mutation in codon 309 resulting in a Pro to Ser substitution. SW480 ...
Manufactured by:Creative Biogene based inShirley, NEW YORK (USA)
Messenger RNA (mRNA) is responsible for transferring genetic information from DNA to proteins. With advances in in vitro transcription (IVT) technology, it has been possible to synthesize mRNA from either plasmid-based DNA templates or DNA PCR amplified from plasmids. mRNA synthesized by IVT methods could be sequence optimized to improve efficiency of translation as well as chemically modified to ...